Aimed at first/second year courses in biochemistry particularly those with a chemical bias, this text is authoritative, comprehensive and reflects current research in biochemistry--especially the advances in molecular and protein structure. There is increased emphasis on Human Disease and more extensive use of molecular techniques. It includes extensive molecular biology material and presents biochemistry from a chemist's perspective. As with the previous edition an annual update Supplement will be published to accompany the text, keeping it as up-to-date as possible. A Solutions Manual is available to accompany this text.

Contents: Introduction and Background: Life; Aqueous Solutions; Thermodynamic Principles: A Review; Biomolecules: Amino Acids; Techniques of Protein Purification; Covalent Structures of Proteins; Three-Dimensional Structures of Proteins; Protein Folding, Dynamics, and Structural Evolution; Haemoglobin: Protein Function in Microcosm; Sugars and Polysaccharides; Lipids and Membranes; Mechanisms of Enzyme Action: Introduction to Enzymes; Rates of Enzymatic Reactions; Enzymatic Catalysis; Metabolism: Introduction to Metabolism; Glycolysis; Glycogen Metabolism; Transport Through Membranes; Citric Acid Cycle; Electron Transport and Oxidative Phosphorylation; Other Pathways of Carbohydrate Metabolism; Photosynthesis; Lipid Metabolism; Amino Acid Metabolism; Energy Metabolism: Integration and Organ Specialisation; Nucleotide Metabolism; The Expression and Transmission of Genetic Information: DNA: the Vehicle of Inheritance; Nucleic Acid Structures and Manipulation; Transcription; Translation; DNA Replication, Repair and Recombination; Viruses: Paradigms for Cellular Functions; Eukaryotic Gene Expression; Molecular Physiology.

Biochemistry 3rd edition DONALD VOET, University of Pennsylvania, USA and JUDITH G. VOET, Swarthmore College, USA Biochemistry is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge. This edition has been updated to reflect the enormous advances in molecular and protein structure Integrated Biochemical Interactions CD

Biochemistry 3rd edition DONALD VOET, University of Pennsylvania, USA and JUDITH G. VOET, Swarthmore College, USA Biochemistry is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge. This edition has been updated to reflect the enormous advances in molecular and protein structure Integrated Biochemical Interactions CD

From the Preface

In the five years since the first edition of ?Biochemistry? was published, the field of biochemistry has continued its phenomenal growth and at an ever-increasing pace. This expansion of our knowledge has been marked not so much by new paradigms, although there have been plenty of those, but by an enormous enrichment of almost every facet in the field. For example, the number of known protein and nucleic acid structures as determined by X-ray and NMR techniques has increased by over fivefold and, moreover, many of these structures have led to seminal advances in our understanding of a particular subfield. Likewise, the state of knowledge has exploded in such subdisciplines as eukaryotic and prokaryotic molecular biology, metabolic control, protein folding, electron transport, membrane transport, immunology, signal transduction, and so on. Indeed, these advances have affected our everyday lives in that they have changed the way that medicine is practised, the way in which food! is produced.

We have reported many of these advances in the second edition of ?Biochemistry? and have thereby substantially changed nearly every section in it. We have, nevertheless, largely maintained the pedagogical framework of the first edition. Consequently, the Preface to the First Edition applies equally well to the Second Edition.

The textbook is accompanies by the following ancillary materials:

- A ?Solutions Manual?, containing detailed solutions for all of the text?s end-of-chapter problems.

- A CD-ROM containing most of the illustrations in the text. With computerized projection equipment, these full-color images can be shown in any prearranged order to provide ?slide shows? to accompany lectures. Alternatively, they can be used to print transparencies.

- A diskette containing KINEMAGES, computer animated color images, of selected proteins and nucleic acids that permit the student to manipulate these macromolecules in three dimensions.

In addition, we shall continue our previous practice of annually publishing ?Supplements to Biochemistry? that summarize the highlights of the preceding year?s biochemical advances. The first of these ~ 80-page ?Supplements? will be available in June 1996 and can be obtained either individually or on a subscription basis.

Finally, we are particularly grateful to the many readers of the First Edition, students and teachers alike, who have taken the trouble to write to us with suggestions on how to improve the textbook and to point out errors they have found. We earnestly hope that the readers of the Second Edition will continue this practice.

Donald Voet Judith G. Voet

2004-07-11 A textbook you will actually read!

This book turned out to be the most used textbook of my undergraduate career. I found it to be informative without being too dry! The diagrams are used to great effect and the chapter on protein folding is superb. This is a great buy for biochemists or undergraduates in chemistry who choose to study some biochem modules etc.