Aimed at first/second year courses in biochemistry particularly those with a chemical bias, this text is authoritative, comprehensive and reflects current research in biochemistry--especially the advances in molecular and protein structure. There is increased emphasis on Human Disease and more extensive use of molecular techniques. It includes extensive molecular biology material and presents biochemistry from a chemist's perspective. As with the previous edition an annual update Supplement will be published to accompany the text, keeping it as up-to-date as possible. A Solutions Manual is available to accompany this text.

Contents: Introduction and Background: Life; Aqueous Solutions; Thermodynamic Principles: A Review; Biomolecules: Amino Acids; Techniques of Protein Purification; Covalent Structures of Proteins; Three-Dimensional Structures of Proteins; Protein Folding, Dynamics, and Structural Evolution; Haemoglobin: Protein Function in Microcosm; Sugars and Polysaccharides; Lipids and Membranes; Mechanisms of Enzyme Action: Introduction to Enzymes; Rates of Enzymatic Reactions; Enzymatic Catalysis; Metabolism: Introduction to Metabolism; Glycolysis; Glycogen Metabolism; Transport Through Membranes; Citric Acid Cycle; Electron Transport and Oxidative Phosphorylation; Other Pathways of Carbohydrate Metabolism; Photosynthesis; Lipid Metabolism; Amino Acid Metabolism; Energy Metabolism: Integration and Organ Specialisation; Nucleotide Metabolism; The Expression and Transmission of Genetic Information: DNA: the Vehicle of Inheritance; Nucleic Acid Structures and Manipulation; Transcription; Translation; DNA Replication, Repair and Recombination; Viruses: Paradigms for Cellular Functions; Eukaryotic Gene Expression; Molecular Physiology.

2004-07-11 A textbook you will actually read!

This book turned out to be the most used textbook of my undergraduate career. I found it to be informative without being too dry! The diagrams are used to great effect and the chapter on protein folding is superb. This is a great buy for biochemists or undergraduates in chemistry who choose to study some biochem modules etc.